FDA-NSAIDS and side effects

Sick Dog

NSAIDS (non-steroidal anti-inflammatories) have their place in the treatment of pain as long as some guidelines are followed. It’s important to be aware that when prescribed with other drugs such as corticosteroids, digoxin, furosamide, phenytoin, oral anticoagulants, other NSAIDS including aspirin, sulfonamides, phenobarbital and some cancer drugs, adverse reactions can occur. Always keep your veterinarian informed as to any drugs or supplements your pet may be taking.

Following is a list of commonly prescribed NSAIDS.

  • Rimadyl (Carprofen) – caution should be taken when used in pets with liver or kidney problems, pregnant dogs, bleeding disorders, geriatric pets. Available only by prescription.
  • Norocarp (Carprofen) – same as Rimadyl
  • Ketoprofen (Anafen) – Do not use with aspirin, corticosteriods or anticoagulants. Available over the counter.
  • Dermamaxx (Deracoxib) – Recommended use – minimum amount for pain management. Available only by prescription.
  • Metacam (Meloxican) – There is a serious risk in use for cats. Available only by prescription.
  • EtoGesic (Etodolac) – Do not use if liver, blood or heart problems are present. Cautious use with other NSAIDS, aspirin, ibuprofen, corticosteroids, some antibiotics. Available only by prescription.
  • Zubrin (Tepoxalin) – Never use with history of bleeding and/or inflammation of the stomach and lining. Use caution with heart, liver or kidney problems, other NSAIDS, corticosteroids, aspirin.

The FDA recommends the following before the administration of any NSAID:

  • All dogs and cats should undergo a thorough history and physical examination before beginning NSAID therapy.
  • Appropriate blood/urine tests should be performed to establish baseline data prior to and periodically during administration of any NSAID.
  • Use with other anti-inflammtory drugs such as NSAIDS and corticosteroids should be avoided.

Common side effects include vomiting, diarrhea, not eating/eating less and lethargy. If your pet experiences any of these potential side effects, STOP administering the medication and contact your veterinarian immediately.

Veterinary NSAIDS may be associated with gastrointestinal ulcers/perforation, liver and kidney toxicity.

Serious side effects associated with the use of NSAI”DS can occur with or without warning and in some cases result in death.

Patients at greatest risk for kidney problems are those that are dehydrated, are on diuretic treatment, or have pre-existing kidney, heart and liver problems.

NSAIDS can cause stomach or intestinal bleeding.

Risks associated with NSAIDS are detailed on package inserts and client information sheets. A client information sheet should always be given to the client with each NSAID prescription. Pet owners should read this information carefully. Owners and veterinarians should carefully consider the potential benefits and risks of using a NSAID and other treatment options before deciding to use a NSAID. Use the lowest effective dose for the shortest duration consistent with individual response.

This is meant just to let you know what the potential side effects of using NSAIDS can be. Your veterinarian and you are the ones who decide what is best for your pet.

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