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Invermectin Sensitivity

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Collie

Invermectin Sensitivity is a disease is which dogs become overly sensitive to certain drugs including invermectin which is found in some heartworm and mite preparations. Certain breeds are particularly prone to this disease: collies, Australian Shepherd Shetland Sheepdogs, Old English Sheepdogs and English Sheepdogs. In other breeds, excessive doses (10-20X the recommended dose) are dangerous. There is no treatment for the disease, but treatment of the symptoms may include :

  • Induction of vomiting
  • Gastric lavage
  • Intravenous fluid and supplemental electrolyte therapy
  • Intravenous feeding or a feeding tube
  • Physical therapy
  • Mechanical ventilation (respirator)
  • Treatment of seizures, with medications such as diazepam or propofol

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