Eosinophilic Granuloma Complex

Cat Vet

An Eosinophil is a type of white blood cell that responds to allergic reactions or parasites. A granuloma is a solid lump of inflammatory cells. There are 3 different skin conditions called Eosinophilic Granuloma Complex, not all of which are granulomas or contain eosinophils. EGC is rare in dogs and more commonly seen in cats and horses.

The Rodent Ulcer (or indolent ulcer) occurs on the upper lip, sometimes on the tongue. These can be per-cancerous and should be checked by your veterinarian.

Eosinophilic Plaque appears as a raised, thick lump of skin usually found on the belly, thigh or throat area. They are itchy and can be diagnosed under a microscope.

Eosinophilic Granuloma can show as a swollen lower lip or a long lesion on the back of the thigh, sometimes on footpads.

Eosinophils are supposed to attack the allergen or parasite invading the body, but the released chemicals can cause damage to the collagen. Collagen is 75% of an animal’s and 70-90% of muscles, tendons, ligaments and other joint supporting tissues and is a powerful antioxidant. It contains 8 essential amino acids, the main protein in teeth, hair and nails and gives strength and elasticity to the skin among its many other jobs in the body.

Treatment is with corticosteroids and in some cases the addition of antibiotics. Severe cases are treated with immunosuppresant drugs.

ECG is a recurring condition usually caused by allergens in the environment. Flea bites are a common cause as well as allergic responses to some foods. Once the allergen is discovered, it can be eliminated. However finding the allergen is not always an easy process.

As with any unusual condition, bring your pet to the veterinarian for examination.

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