As early as the end of this year, 2012, a product to neuter male dogs without surgery will be available in the U.S. The drug is presently in use in Bolivia, Columbia, Mexico and Panama. It will be known in the U.S. by the brand name, Zeuterin.
The FDA has approved its use in dogs 3-10 months of age. Zeuterin is an injectable dispensed only by veterinarians trained and licensed by the company, Ark Sciences. Injections do not require anesthesia and dogs are released shortly after the procedure. Ark Sciences has a waiting list which it will serve on a first-come, first-served basis. If you wish, you may add your dog to the list.
The formula, zinc glutanate neutralized with arginine, was originally approved by the FDA in 2003 when it was produced by Addison Labs under the trade name Neutersol. Financial difficulties led to problems and Ark Sciences has since acquired all rights to the Neutersol technology, improving the product and delivery.
Zinc glutanate is injected into an area of the testes and acts as a spermicide, reducing the size of the testicles and causing permanent sterilization.
In a study of 270 puppies, reactions occurred in a small number of dogs. Reactions included pain, irritation, other scrotal problems, vomiting, diarrhea, lethargy, etc.
As with any drug, there arr always a certain number of side effects which hopefully Ark Sciences will continue to monitor and be able to improve the product.